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Treating Palmar Hyperhidrosis with Botox: Benefits, Limitations, and Side Effects

Updated: April 10, 2023
By: Lauren Siso, LE, ALP

Lauren Siso, LE, ALP

Lauren Siso, LE, ALP

Lauren is the proud owner of ELLEMES Medical Spa with over a decade of experience in the Atlanta, GA area. She is recognized for her outstanding work with accolades such as Best Esthetician in Atlanta by Jezebel Magazine and Best Aesthetic Influencer by Dermascope Magazine.

woman holding up botox


Palmar hyperhidrosis, more commonly known as excessive sweating of the palms and soles of the feet, is a condition that can be truly debilitating. For those who suffer from this condition, it can be incredibly embarrassing and cause a great deal of stress. People who suffer from palmar hyperhidrosis struggle to find relief and effective treatments. As a medical spa owner, I often get asked, “Can Botox be used for treating palmar hyperhidrosis?” The answer is yes! In fact, Botox is one of the most common treatments for palmar hyperhidrosis. In this article, I’ll discuss the specifics of how Botox can be used to treat this condition, as well as outlining the limitations and side effects of this treatment.

How Does Botox Treat Palmar Hyperhidrosis?

botox treatment

The nerve endings in the hands and feet are responsible for the production of sweat. When these nerve endings are blocked, it reduces the amount of sweat that is produced. Botox works by blocking these nerve endings and inhibiting the production of sweat in the hands and feet. Injections of Botox are administered directly into the skin of the palms and soles of the feet. The amount of Botox needed to treat palmar hyperhidrosis will vary from patient to patient, but generally, the number of injections range from 10 to 30.

What are the Benefits of Botox Treatment for Palmar Hyperhidrosis?

Botox injections offer an effective, long-term solution for palmar hyperhidrosis. Studies have shown that Botox can reduce sweat production by up to 80%. This means that people who suffer from palmar hyperhidrosis can gain relief from the embarrassing and uncomfortable symptoms of excessive sweating. Botox treatments are also relatively non-invasive and can be administered quickly in a doctor’s office.

woman receiving botox treatment

What are the Limitations of Botox Treatments?

Although Botox is an effective treatment for palmar hyperhidrosis, it is not a permanent solution. The effects of the treatment will generally last for between three and six months. After that, patients will need to receive additional treatments in order to maintain the results. Additionally, Botox treatments can be expensive and may not be covered by insurance.

Are There Any Side Effects?

As with any medical treatment, there are always potential side effects. The most common side effect of Botox is localized pain and swelling at the injection site. Some patients may also experience temporary numbness or weakness in their hands or feet. In rare cases, there may also be skin discoloration or hypersensitivity at the injection site.


Botox is an effective and long-lasting treatment for palmar hyperhidrosis. Injections of Botox are administered into the skin of the palms and soles of the feet in order to reduce the amount of sweat produced. The effects of the treatment generally last for three to six months and can offer patients significant relief from the symptoms of palmar hyperhidrosis. However, it is important to note that Botox treatments can be expensive and there may be some side effects associated with it. If you think that Botox might be right for you, I recommend consulting with a doctor to discuss the best treatment plan for you.

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Staff Spotlight

Lauren Siso, Esthetician

Lauren has been medical aesthetician and laser practitioner for over 10 years and is passionate about helping her clients achieve their best skin possible. Lauren truly believes that everyone deserves to feel confident in their own skin and is dedicated to helping her clients achieve that goal!

lauren siso performing dermaplaning treatment
Lauren Siso, Medical Aesthetician at ELLEMES Medical Spa