Salmon DNA
Facial
PDRN microneedling for collagen, texture, and deep hydration.


PDRN + Microneedling
This treatment pairs SkinPen microneedling with LUMICEN salmon DNA serum — a concentrated blend of polydeoxyribonucleotides (PDRN), vitamins, amino acids, and minerals.
Microneedling creates microchannels that allow the PDRN and nutrients to penetrate the dermis. These DNA fragments signal cells to regenerate collagen, produce elastin, and accelerate tissue repair.
Addresses fine lines, uneven texture, acne scars, and chronic dryness. The PDRN component also reduces post-procedure healing time compared to standard microneedling alone.
What It Does

Accelerated Tissue Repair
PDRN activates the A2A adenosine receptor pathway, accelerating cell turnover and reducing microneedling recovery time.

Scar & Line Reduction
Microneedling breaks down old scar tissue while PDRN drives new collagen formation, improving the appearance of acne scars, fine lines, and uneven texture over successive sessions.

Dermal Hydration
Vitamins, minerals, and hyaluronic acid are delivered directly into the dermis through microchannels, restoring the moisture barrier at a level topical products cannot reach.
Skin Concerns We Treat
The Salmon DNA Facial addresses a range of texture, tone, and hydration issues. Here's what it targets and when it's the right choice.
Pitted and rolling acne scars result from collagen loss during the healing of inflammatory acne. SkinPen microneedling breaks down the fibrous bands anchoring scar tissue, while PDRN drives new collagen formation to fill the depressions from within. Multiple sessions produce cumulative improvement. For patients with active acne, clearing breakouts with a targeted facial regimen or chemical peel before beginning microneedling is typically recommended.
Fine lines develop as collagen and elastin production slows with age. The controlled micro-injuries from SkinPen trigger the wound-healing cascade, while PDRN accelerates the collagen remodeling phase. The result is firmer, smoother skin that develops over 2–3 months per session. For deeper dynamic wrinkles caused by repeated muscle movement, Botox or Dysport can be used as a complement to address both the structural and muscular components.
Surface-level dryness often persists because topical moisturizers cannot penetrate deeply enough to restore the dermal moisture barrier. Microneedling creates microchannels that deliver the LUMICEN serum — including hyaluronic acid, vitamins, and amino acids — directly into the dermis. This restores hydration at a structural level rather than just coating the surface. For ongoing hydration maintenance between sessions, a HydraFacial is an effective complement.
Rough, uneven skin texture is typically the result of accumulated dead skin cells, sun damage, and uneven collagen distribution. Microneedling triggers controlled resurfacing from within, while PDRN promotes uniform collagen formation across the treatment area. As each session builds on the last, patients see progressively smoother, more even skin. Alternating with a MOXI laser facial between microneedling sessions can further refine tone and texture.
Cumulative UV exposure breaks down collagen, thickens the stratum corneum, and causes uneven melanin distribution — leaving skin looking dull and aged. PDRN's tissue-repair signaling helps reverse this damage at the cellular level, while microneedling stimulates the turnover of damaged cells. The vitamin and mineral complex in the LUMICEN serum provides antioxidant support during the healing phase. For active hyperpigmentation, a VI Peel can target melanin production directly.
The neck and décolletage are prone to crepiness, fine lines, and laxity because the skin in these areas is thinner and receives less attention in daily skincare. The Salmon DNA Facial can be extended to cover face, neck, and chest in a single session — delivering PDRN and nutrients to all three zones. This is especially effective for patients whose neck and chest show more visible signs of aging than their face. For structural volume loss in these areas, dermal fillers can address deeper deficits.
What to Expect
A Salmon DNA Facial appointment takes approximately 60–75 minutes depending on the treatment area. Here's what happens at each step.
Post-Treatment Tips
Avoid direct sun exposure and use mineral SPF for at least 7 days. No makeup for 12 hours. Avoid retinols, AHAs/BHAs, and exfoliants for 72 hours. Skip strenuous exercise for 24 hours. Keep skin hydrated with a gentle, fragrance-free moisturizer. For full guidance, visit our post-care instructions.
Treatment Options
Available for face, neck, and chest. Choose your treatment area based on where you want to target collagen production, scar reduction, and hydration.
Face
Face & Neck
Face, Neck & Chest
Who Performs This Treatment

Lauren Siso

Jaycee Zotti

Christian Carter
How Often to Treat
Collagen remodeling is cumulative — each session builds on the results of the last. Here's how most patients schedule their Salmon DNA Facial appointments.
Between Salmon DNA Facial sessions, treatments like HydraFacial or a Deluxe Facial can maintain hydration and clarity without interfering with the collagen remodeling process. View all ELLEMES treatments.
Salmon DNA Facial vs. Standard Microneedling
Both treatments use SkinPen microneedling to stimulate collagen. The difference is what goes into the microchannels. Here's how the Salmon DNA Facial compares to standard microneedling with hyaluronic acid serum.
Both options use the same FDA-cleared SkinPen device. The Salmon DNA Facial adds the PDRN serum to enhance collagen signaling and speed recovery. Your aesthetician can recommend the right option based on your skin concerns and budget during a consultation. Learn more about standard microneedling at ELLEMES.
Salmon DNA Reviews
"The Salmon DNA Facial made a real difference. My skin has never looked so plump and hydrated. The healing was noticeably faster compared to regular microneedling."
"I struggled with acne scars for years. After combining microneedling with the Salmon DNA serum, my texture is so much smoother. Lauren is great."
"I was nervous about microneedling, but Jaycee made it easy. The PDRN serum gave me a glass-skin glow that lasted for weeks."
"The Salmon DNA treatment left my skin feeling firm and looking healthy. Happy with the results."
"Christian recommended the Salmon DNA facial for my dull skin and fine lines. The results have been great and downtime was minimal."
"The Salmon DNA facial evened out my skin tone and my face feels soft and refreshed."
"The combination of microneedling and the salmon serum healed my skin faster than regular microneedling. Pleased with the results."
"The staff at ELLEMES are knowledgeable. They explained the science behind PDRN and my skin looks noticeably healthier."
"My acne scars have faded noticeably after just two sessions. A solid experience with real results."
"The glass skin effect is real. Would recommend this to anyone dealing with dehydration and fine lines."
Pairs Well With
The Salmon DNA Facial targets collagen and deep tissue repair. These treatments address complementary concerns — surface turnover, tone, and maintenance hydration.

Deluxe Facial
A maintenance facial between Salmon DNA sessions. Keeps the surface clear and hydrated without added downtime.

VI Peel
Accelerates cell turnover and addresses post-inflammatory hyperpigmentation that microneedling alone may not fully resolve.

MOXI Laser
A low-downtime laser that targets early sun damage and refines overall tone between microneedling sessions.

HydraFacial
Alternate with Salmon DNA sessions for consistent deep cleansing and surface hydration with no downtime.
Common
Questions
What to know before booking the Salmon DNA Facial at ELLEMES.

This facial pairs SkinPen microneedling with LUMICEN salmon DNA serum (PDRN, vitamins, amino acids, minerals, and hyaluronic acid). The microchannels allow the nutrients and DNA fragments to penetrate the dermis, signaling cells to regenerate collagen, produce elastin, and repair tissue.
For lasting results, a series of 3–6 sessions spaced about 4 weeks apart is recommended. Many patients notice improved hydration and texture after the first treatment.
Expect mild redness and warmth for 24–48 hours, similar to a sunburn. The PDRN serum helps accelerate healing compared to standard microneedling alone.
A topical numbing cream is applied before the procedure. Most patients describe the sensation as mild prickling rather than pain.
Adults dealing with fine lines, uneven texture, acne scars, hyperpigmentation, or persistent dryness. Safe for most skin types. Not recommended during active infections, severe acne flares, or for those with severe fish allergies.
Most patients notice improved hydration and softer texture within 1–2 weeks. Collagen remodeling continues for 2–3 months after each session, so results compound over time.
Yes. Microneedling breaks down old scar tissue while the PDRN drives new collagen formation to fill and smooth pitted scars over successive sessions.
When You're Ready
Book a consultation to discuss your skin concerns and determine if the Salmon DNA Facial is the right treatment for your goals.
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