Ariessence
Pure PDGF+
Lab-grade growth factors. No blood draw required.
What PDGF+ Does
Ariessence Pure PDGF+ delivers pharmaceutical-grade platelet-derived growth factor combined with hyaluronic acid. It supports healing, stimulates collagen production, and smooths fine lines.
Because it's lab-manufactured rather than blood-derived, the concentration is consistent and the dosage is predictable — unlike PRP or PRF, which vary from draw to draw.
It works well as a standalone treatment for texture and tone, or as a recovery accelerant after laser and microneedling procedures. No blood draw, minimal downtime.
The Benefits
Collagen Production
Activates your body's natural repair processes, promoting tissue regeneration and faster healing — especially after procedures.
Deep Hydration
The hyaluronic acid carrier delivers sustained moisture while growth factors improve firmness, smooth fine lines, and refine texture.
Gradual, Lasting Results
Produces gradual improvement without volume distortion. Low downtime with reduced redness compared to blood-derived alternatives.
Skin Concerns We Treat
PDGF+ addresses a range of skin quality concerns through growth-factor-driven collagen stimulation — without the variability of a blood draw. Here's what it targets.
Dark circles and hollowing under the eyes are caused by thinning skin, visible vasculature, and volume loss in the tear trough area. PDGF+ thickens the dermal layer by stimulating collagen production, reducing the translucency that makes vessels and pigment visible. For patients with significant hollowing in addition to skin quality issues, PRF Undereye or PRF EZ Gel can address the volume component while PDGF+ targets the skin itself.
Fine lines form as collagen and elastin production slows with age. PDGF+ delivers a standardized dose of growth factors that activate fibroblasts and stimulate new collagen synthesis, gradually smoothing fine lines over multiple treatments. For dynamic wrinkles caused by repeated muscle movement, Botox or Dysport can be combined to address both the muscular and structural components.
As the dermis loses collagen density, skin becomes thinner and less resilient — contributing to a crepey texture and reduced firmness. PDGF+ supports the structural matrix by promoting new collagen and elastin at the dermal level. For patients with more advanced laxity, combining PDGF+ with Vivace RF Microneedling can provide deeper tissue remodeling while the growth factors accelerate recovery.
Rough texture, enlarged pores, and uneven tone are often the result of accumulated sun damage, environmental exposure, and slowed cell turnover. PDGF+ stimulates cellular renewal and collagen remodeling that smooths the skin surface over time. Pairing PDGF+ as an add-on to SkinPen microneedling or a chemical peel can amplify texture improvement.
PDGF+ is frequently used as an add-on to laser resurfacing, microneedling, and RF treatments to accelerate the healing process. The growth factors reduce inflammation, support tissue repair, and can shorten the visible recovery window. Common pairings include MOXI laser, BBL Photofacial, and Vivace RF Microneedling.
Skin that appears flat, tired, or dehydrated often lacks both moisture and the cellular activity needed for healthy turnover. The hyaluronic acid carrier in PDGF+ delivers immediate hydration while the growth factors support deeper tissue renewal over the following weeks. A HydraFacial or Deluxe Facial between sessions can maintain clarity and moisture.
What to Expect
A standalone PDGF+ treatment takes approximately 30–45 minutes. When used as an add-on to microneedling or laser, it's incorporated into the existing session time.
Post-Treatment Tips
Use mineral SPF 30+ daily for at least 2 weeks. Avoid retinoids, active acids, and exfoliants for 3–5 days post-treatment. No makeup for 12–24 hours after injection. Avoid saunas, steam rooms, and strenuous exercise for 24–48 hours. Keep skin hydrated with a gentle moisturizer. For full guidance, visit our post-care instructions.
Treatment Options
PDGF+ can be used as a standalone injection or added to microneedling, laser, or RF treatments to accelerate results. Your provider will recommend the right approach during a consultation.
Stand-Alone PDGF+
Package of 3 — Save 10%
Package of 5 — Save 15%
PDGF+ Add-On
• Undereye PRF EZ Gel — $900
• PRF Undereye — $650
Who Performs This Treatment
Thao Nguyen, RN
How Often to Treat
PDGF+ produces cumulative results — each session builds on the collagen and tissue quality established by the previous one. Your provider will recommend a plan based on your starting point and goals.
Between PDGF+ sessions, treatments like HydraFacial or a Deluxe Facial can maintain hydration and clarity. For deeper regenerative pairing, ask about PRF EZ Gel or Salmon DNA Facial. View all ELLEMES treatments.
PDGF+ vs. PRP & PRF
All three treatments use growth factors to stimulate collagen and tissue repair. The key difference is the source: PDGF+ is lab-manufactured at a consistent concentration, while PRP and PRF are derived from your own blood and vary from patient to patient.
PDGF+ and PRP/PRF are not interchangeable — each has strengths depending on the concern being treated. Some patients benefit from both in different areas of the face. For an alternative regenerative approach using polynucleotide technology, ask about the Salmon DNA Facial (PDRN). Your provider will recommend the right option during a consultation.
Common
Questions
What to know before booking an Ariessence PDGF+ treatment.
Ariessence Pure PDGF+ is a pharmaceutical-grade formulation of platelet-derived growth factor (PDGF-BB) combined with hyaluronic acid. Unlike PRP or PRF, it's lab-manufactured — no blood draw required — and delivers a consistent, high-purity dose of growth factors every time.
No. PDGF+ stimulates your body's own collagen, elastin, and tissue regeneration. Improvements are gradual — better firmness, texture, and tone — rather than adding physical volume like hyaluronic acid fillers.
Fine lines and wrinkles, thinning or lax skin (especially under-eyes), texture irregularities, dark circles, and post-procedure recovery when paired with treatments like microneedling or lasers.
Some improvement may be noticeable after one session, especially in brightness. For more lasting results, most patients benefit from 2–3 treatments spaced several weeks apart. Results continue developing over time.
Minimal. You might experience mild redness, swelling, tenderness, or slight bruising at the treatment area. These effects typically resolve within a day or two.
Yes. PDGF+ is often used as an add-on to microneedling or laser treatments to accelerate healing, support deeper results, and reduce post-procedure inflammation.
Yes. Because it's a recombinant growth factor — not derived from donor blood or human tissue — it's generally safe for all skin tones and types with very low risk of allergic reaction.
Avoid strong exfoliants, retinoids, or active acids for a few days before treatment. After, keep the area clean, moisturized, and use sunscreen daily. Your provider will give you a specific aftercare plan at your appointment.
When You're Ready
Schedule a consultation and we'll recommend the right approach based on your skin, your concerns, and your timeline.
Book a Consultation